1. To become dispirited from loss of hope or in presence of difficulty seemingly insuperable; to lose hope.

Nuttall's Standard dictionary of the English language By Nuttall, P.Austin

• despone,
• sespond,
• xespond,
• cespond,
• fespond,
• respond,
• eespond,
• dwspond,
• dsspond,
• ddspond,
• drspond,
• d4spond,
• d3spond,
• despoind,
• desponed,
• desponde,
• despont,
• Despand,
• dispond,
• despong

• descend,
• despondent,
• Despina,
• depend,
• respond,
• despain,
• despoina.

The adverb form of the word "despond" is "despondently".

The adjective form of the word "despond" is "despondent".

The plural form of the word "despond" is "desponds".

The singular form of the word "despond" is "despondency"